The fire engulfed a significant portion of the hotel structure.
The cause of the fire is currently unknown, but it was reported to have started around 4:30 am on Monday.
Fire service personnel from Delta and Anambra states have been deployed to the scene to tackle the blaze.
Efforts are underway to bring the situation under control.
The Anambra State Fire Chief, Martins Agbili, could not be reached for immediate comments, while the state police spokesman, DSP Tochukwu Ikenga, confirmed the incident and assured that the situation was being handled.
Further details about the extent of the damage and any injuries or casualties are yet to be provided.
“The situation is under control. The fire started around 4:30 am on Monday and when we got the information, our men were quickly mobilised to the scene and they condoned off the area to avoid any case of vandalism.
“No loss of life and the men of the fire service are on the ground controlling the situation and managing the fire,” Ikenga said.